Shape abnormalities of caudate nucleus in schizotypal personality disorder
نویسندگان
چکیده
منابع مشابه
Shape abnormalities of caudate nucleus in schizotypal personality disorder.
BACKGROUND Previously, we reported abnormal volume and global shape in the caudate nucleus in schizotypal personality disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as local correlations with behavioral measures. METHODS Thirty-two female and 15 male SPDs, and 29 female and 14 male normal controls (NCLs), underwen...
متن کاملShape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorder.
BACKGROUND We measured the shape of the head of the caudate nucleus with a new approach based on magnetic resonance imaging (MRI) in schizotypal personality disorder (SPD) subjects in whom we previously reported decreased caudate nucleus volume. We believe MRI shape analysis complements traditional MRI volume measurements. METHODS Magnetic resonance imaging scans were used to measure the shap...
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OBJECTIVE Patients with schizophrenia speak with blunted vocal affect but little is known regarding the prosody of persons with schizotypal personality disorder (SPD). This work examined expressive prosody in SPD, its relationship to brain structure, and outlined a framework for measuring elements of prosody in clinical populations. METHODS Twenty-eight antipsychotic-naïve SPD subjects were m...
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BACKGROUND The caudate nucleus might contribute to the psychopathological and cognitive deficits observed in schizotypal personality disorder (SPD), a schizophrenia spectrum disorder. Here we focused on female patients, because this group is underrepresented in studies of SPD and schizophrenia, and we might learn more about the caudate and clinical and cognitive impairments that are unique to f...
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Prior diffusion tensor imaging (DTI) studies examining schizotypal personality disorder (SPD) and schizophrenia, separately have shown that compared with healthy controls (HCs), patients show frontotemporal white matter (WM) abnormalities. This is the first DTI study to directly compare WM tract coherence with tractography and fractional anisotropy (FA) across the schizophrenia spectrum in a la...
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ژورنال
عنوان ژورنال: Schizophrenia Research
سال: 2009
ISSN: 0920-9964
DOI: 10.1016/j.schres.2008.11.012